Anja Wolter
Coordonnées(Éditer)
- Adresse professionnelle :
Leibniz Institut für Festkörper- und Werkstoffforschung
Abt. Magnetische und Akustische Resonanzen
Helmholtzstr. 20
01069 Dresden
- E-mail : a.wolter@ifw-dresden.de
Magnetic Carbon Nanotubes for Biomedical Applications(Éditer)
There is a fastly increasing interest in applying nanoscaled magnets as small probes which interact with external magnetic fields. For biomedical applications, such nanoparticles are transferred into the cells in order to manipulate and to sensor biological systems noninvasively. One promising approach to realize such functional elements is based on filling carbon nanotubes (CNT) with tailored materials. In this case, therapeutically or diagnostically active material is encapsulated by a protecting carbon shell, e.g. nanoscaled magnetic heaters, drug carrier systems and sensors. Beyond the shielding effect against biological environment, the carbon coating offers an interface for exohedral functionalisation with suitable (bio-) molecules.
In this lecture different synthesis and filling routes of CNT are reported and their structural and magnetic properties are presented. The feasibility of applying filled CNT in biomedicine is shown by their successful transfer into (cancer) cells and for two different examples: (i) Magnetic filled CNT offer the potential for hyperthermia applications by applying alternating magnetic fields. (ii) Insertion of nuclear magnetic resonance (NMR) active substances provides nanoscaled markers and sensors, e.g. non-invasive temperature control by virtue of a carbon-wrapped nanoscaled thermometer is possible.